As the global pharmaceutical industry continues to evolve and expand, the United States remains a dominant force, housing some of the most influential and innovative specialty pharmaceutical manufacturers. Recognized for their expertise in developing and manufacturing complex drugs and biologics to treat rare and complex diseases, these companies have made significant contributions to the healthcare sector. Here, we present a comprehensive overview of the top 10 specialty pharmaceutical manufacturers in the US, exploring their sector, year founded, annual revenue, short description, and a link to their website.
The specialty pharmaceutical sector in the US is characterized by companies that focus on the development, production, and marketing of specialized drugs and treatments for specific medical conditions. These companies often specialize in serving niche markets and catering to patients with complex needs, such as those with rare diseases, cancer, autoimmune disorders, and other serious health conditions. With a strong emphasis on research and innovation, these manufacturers play a crucial role in advancing medical science and improving patient outcomes.
1. Amgen
– Sector: Biotechnology
– Year Founded: 1980
– Annual Revenue: $24.0 billion (2020)
– Description: Amgen is a leading biotechnology company that focuses on developing innovative therapies for patients suffering from serious illnesses. Their portfolio includes biologic medications used in cancer treatment, supportive care, and inflammation conditions.
– Website: [Amgen](https://www.amgen.com)
2. Gilead Sciences
– Sector: Biotechnology
– Year Founded: 1987
– Annual Revenue: $22.4 billion (2020)
– Description: Gilead Sciences is renowned for its advancements in HIV/AIDS, liver diseases, and hematology. The company is dedicated to creating innovative medicines to address unmet medical needs and improve patient care around the world.
– Website: [Gilead Sciences](https://www.gilead.com)
3. Regeneron Pharmaceuticals
– Sector: Biotechnology
– Year Founded: 1988
– Annual Revenue: $8.5 billion (2020)
– Description: Regeneron Pharmaceuticals focuses on the discovery, development, and commercialization of medicines for serious diseases. Their efforts have resulted in groundbreaking treatments for eye diseases, allergic conditions, and cancer.
– Website: [Regeneron Pharmaceuticals](https://www.regeneron.com)
4. BioMarin Pharmaceutical
– Sector: Biotechnology
– Year Founded: 1997
– Annual Revenue: $1.9 billion (2020)
– Description: BioMarin Pharmaceutical specializes in developing and commercializing innovative biopharmaceuticals for rare genetic diseases that have significant unmet medical needs. The company has made significant strides in the field of enzyme replacement therapies and gene therapies.
– Website: [BioMarin Pharmaceutical](https://www.biomarin.com)
5. Vertex Pharmaceuticals
– Sector: Biotechnology
– Year Founded: 1989
– Annual Revenue: $6.2 billion (2020)
– Description: Vertex Pharmaceuticals is a global biotechnology company that focuses on creating transformative medicines for people with serious diseases. The company’s core efforts are directed towards the treatment of cystic fibrosis and other serious pulmonary conditions.
– Website: [Vertex Pharmaceuticals](https://www.vrtx.com)
6. Incyte Corporation
– Sector: Biotechnology
– Year Founded: 2002
– Annual Revenue: $2.5 billion (2020)
– Description: Incyte Corporation is committed to the discovery and development of innovative medicines to meet the needs of patients with cancer and other serious diseases. The company has garnered attention for its notable advancements in the field of oncology.
– Website: [Incyte Corporation](https://www.incyte.com)
7. Aimmune Therapeutics
– Sector: Biotechnology
– Year Founded: 2011
– Annual Revenue: $220.0 million (2019)
– Description: Aimmune Therapeutics is dedicated to improving the lives of people with potentially life-threatening food allergies through the development of innovative, desensitizing treatments. The company’s focus on addressing unmet medical needs has been pivotal in this specialized niche.
– Website: [Aimmune Therapeutics](https://www.aimmune.com)
8. Horizon Therapeutics
– Sector: Biotechnology
– Year Founded: 2008
– Annual Revenue: $2.2 billion (2020)
– Description: Horizon Therapeutics is committed to developing and commercializing innovative medicines that address unmet treatment needs for rare and rheumatic diseases. The company’s work has led to significant advancements in treating disorders that were previously underserved.
– Website: [Horizon Therapeutics](https://www.horizontherapeutics.com)
9. Mallinckrodt Pharmaceuticals
– Sector: Pharmaceuticals
– Year Founded: 1867
– Annual Revenue: $2.6 billion (2019)
– Description: Mallinckrodt Pharmaceuticals is a global specialty pharmaceutical company with a focus on the development and marketing of specialty therapies in autoimmune and rare diseases. The company maintains a deep commitment to addressing rare and severe conditions.
– Website: [Mallinckrodt Pharmaceuticals](https://www.mallinckrodt.com)
10. Portola Pharmaceuticals
– Sector: Biotechnology
– Year Founded: 2003
– Annual Revenue: $227.6 million (2019)
– Description: Portola Pharmaceuticals is dedicated to discovering, developing, and commercializing life-saving therapies for patients with significant unmet medical needs. The company’s contributions in the field of anticoagulation have been particularly notable.
– Website: [Portola Pharmaceuticals](https://www.portola.com)
The top 10 specialty pharmaceutical manufacturers in the US have consistently demonstrated their commitment to scientific innovation, patient care, and addressing unmet medical needs. Their contributions have been instrumental in transforming the landscape of healthcare, particularly in the treatment of rare and complex diseases. With ongoing research and development efforts, these companies continue to lead the way in pioneering therapies that have the potential to enhance and prolong the lives of countless individuals.
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